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In the last decades, the amount of sufferers referred for allogeneic hematopoietic cell transplantation has dropped significantly,133 even so the technique needs to be advised to younger/match sufferers in whom BCR/BCL2 inhibitor remedy fails, especially in These with TP53
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In spite of all the latest therapeutic advances, a proportion of sufferers will nevertheless fail to respond and will be thought of for curative therapy. Presently, only allogeneic hematopoietic mobile transplantation might be deemed possibly curative, but It is additionally related to significant morbidity and mortality.
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